Docteur Claire GOZALO

• « Urinary methotrexate dosage in rheumatoid arthritis, in patients treated for at least 6 months: a potential marker of adherence. »

Théate N, Geoffroy M, Kanagaratnam L, Gozalo C, Charlot I, Bolko L, Hittinger-Roux A, Djerada Z, Salmon JH.
RMD Open. 2024 May 20;10(2):e004024. doi: 10.1136/rmdopen-2023-004024.PMID: 38772677 

• « Simultaneous quantification of 55 psychotropic drugs and metabolites in human plasma with a fast UPLC-MS/MS method. »

Konecki C, Hadjoudj J, Tralongo F, Haudecoeur C, Gozalo C, Fouley A, Marty H, Feliu C, Djerada Z..
Biomed Pharmacother. 2023 Dec 31;169:115918. doi: 10.1016/j.biopha.2023.115918. Epub 2023 Nov 25.PMID: 38007935 

• « Management of a delayed acetaminophen exposure after massive overdose : A case study »

Konecki C, Djerada Z, Azzouz B, Gozalo C, Fouley A, Cazaubon Y, Feliu C.
Therapie. 2023 Nov-Dec ;78(6) :751-754. doi: 10.1016/j.therap.2022.12.006.

• « A new pharmacokinetic model of urinary methotrexate to assess adherence in rheumatoid arthritis »

Geoffroy M, Gozalo C, Konecki C, Pauvele L, Hittinger A, Pastorel N, Feliu C, Salmon JH, Djerada Z.
Biomed Pharmacother. 2023 Oct 19 ;168:115620. doi: 10.1016/j.biopha.2023.115620. Online ahead of print.

• « Renal impairment and abnormal liver function tests in pre-therapeutic phenotype-based DPD deficiency screening using uracilemia : a comprehesive population-based study in 1138 patients »

Callon S, Brugel M, Botsen D, Royer B, Slimano F, Feliu C, Gozalo C, Konecki C, Devie B, Carlier C, Daire V, Laurès N, Perrier M, Djerada Z, Bouche O.
Ther Adv Med Oncol. 2023 Jan 10;15:17588359221148536. doi: 10.1177/17588359221148536. eCollection 2023. 

• « Development and validation of a non-targeted screening method for most psychoactive, aalgesic, anaesthetic, anti-diabetic, anti-coagulant and anti-hypertensive drugs in human whole blood and plasma using high-resolution mass spectrometry »

Feliu C, Konecki C, Cazaubon Y, Binet L, Vautier D, Fouley A, Gozalo C, Djerada Z.
Pharmaceuticals (Basel). 2023 Jan 4;16(1) :76

• « Impact of guidelines regarding dihydropyrimidine dehydrogenase (DPD) deficiency screening using uracil-based phenotyping on the reduction of severe side effect of 5-fluorouracil-based chemotherapy : a propension score analysis »

Laures N, Konecki C, Brugel M, Giffard AL, Abdelli N, Botsen D, Carlier C, Gozalo C, Feliu C, Slimano F, Djerada Z, Bouche O.
Pharmaceutics. 2022 Oct 6 ;14(10);2119

• « Incidence, associated factors,and effect on renal function of amoxicillin crystalluria in patients receiving high doses of amoxicillin (The Cristamox study) : a cohort study »

Demotier S, Limelette A, Charmillon A, Baux E, Parent X, Mestrallet S, Pavel S, Servettaz A, Dramé M, Muggeo A, Wynckel A, Gozalo C, Taam MA, Fillion A, Jaussaud R, Trenque T, Piroth L, Bani-Sadr F, Hentzien M ; Cristamox study-group.
EClinicalMedicine. 2022 Mar 12 ;45 ;101340

• « Quantification of 15 antibiotics widely used in the critical care unit with a LC-MS/MS system : an easy method to perform a daily therapeutic drug monitoring »

Feliu C, Konecki C, Candau T, Vautier D, Haudecoeur C, Gozalo C, Cazaubon Y, Djerada Z.
Pharmaceuticals (Basel). 2021 Nov 24;14(12) :1214

• « Alveolar hemorrhage due to marijuana smokingusing water pipe made with plastic bottle: casereport and narrative review of the literature »

Toquet S, Cousson J, Choiselle N, Gozalo C, Giusti D, Bani-Sadr F, N’Guyen Y.
Inhalation Toxicology, DOI: 10.1080/08958378.2021.1939465

• « The antidiabetic drug glibenclamide exerts direct retinal neuroprotection »

Berdugo M, Delaunay K, Naud MC, Guegan J, Moulin A, Savoldelli M, Picard E, Radet L, Jonet L, Djerada Z, Gozalo C, Daruich A, Beltrand J, Jeanny JC, Kermorvant-Duchemin E, Crisanti P, Polak M, Behar-Cohen F. 
Transl Res. 2021 Mar;229:83-99. doi: 10.1016/j.trsl.2020.10.003. Epub 2020 Oct 17.

• « Quantification of methadone, buprenorphine, naloxone, opioids, and their derivates in whole blood by liquid chromatography-high-resolution mass spectrometry: Analysis of their involvement in fatal forensic cases. »

Feliu C, Konecki C, Binet L,Vautier D, Haudecoeur C, Oget O, Fouley A, Marty H, Gozalo C, Cazaubon Y, Djerada Z.
J Chromatogr B Analyt Technol Biomed Life Sci. 2020 Sep 1 ; 1152 :122226

• Glibenclamide oral suspension: Suitable and effective in patients with neonatal diabetes.

Beltrand J, Baptiste A, Busiah K, Bouazza N, Godot C, Boucheron A, Djerada Z, Gozalo C, Berdugo M, Tréluyer JM, Elie C, Polak M; GLID-KIR study group.
Pediatr Diabetes, 2019, 20, 246-254

• « Population pharmacokinetics of articaine with 1:200,000 epinephrine during third molar surgery and simulation of high-dose regimens. »

Cazaubon Y, Mauprivez C, Feliu C, Binet L, Oget O, Gozalo C, Djerada Z.
Eur J Pharm Sci. 2018 Mar 1;114:38-45

• « Therapeutic drug monitoring of mitotane: Analytical assay and patient follow-up. »

Feliu C, Cazaubon Y, Guillemin H, Vautier D, Oget O, Millart H, Gozalo C, Djerada Z.
Biomed Chromatogr. 2017 Nov;31(11)

• « Drowsiness and uncommon fever in a child after cannabis ingestion. »

Feliu C, Cazaubon Y, Fouley A, Guillemin H, Millart H, Gozalo C, Djerada Z.
Ann Biol Clin (Paris). 2017 Aug 1;75(4):462-465

• « A Slight Smell of Lemon. »

Feliu C, Cazaubon Y, Fouley A, Guillemin H, Gozalo C, Djerada Z.
Ther Drug Monit. 2017 Jun;39(3):205-207

• « False negative on a proven involuntary intoxication in two children with lorazepam. »

Feliu C, Guillemin H, Gozalo C, Fouley A, Marty H, Millart H, Djerada Z.
Ann Biol Clin (Paris). 2017 Feb 1;75(1):83-86

• « Evaluation of the pharmacokinetics of glibenclamide tablet given, off label, orally to children suffering from neonatal syndromic hyperglycemia. »

Bouazza N, Djerada Z, Gozalo C, Busiah K, Beltrand J, Berdugo M, Urien S, Treluyer JM, Polak M.
Eur J Clin Pharmacol. 2016 Nov;72(11):1373-1379

• « Analytical interference in the therapeutic drug monitoring of methotrexate. »

Oudart JB, Marquet B, Feliu C, Gozalo C, Djerada Z, Millart H.
Ann Biol Clin (Paris). 2016 Jun 1;74(3):333-7

• « Sulfonylurea Therapy Benefits Neurological and Psychomotor Functions in Patients With Neonatal Diabetes Owing to Potassium Channel Mutations. »

Beltrand J, Elie C, Busiah K, Fournier E, Boddaert N, Bahi-Buisson N, Vera M, Bui-Quoc E, Ingster-Moati I, Berdugo M, Simon A, Gozalo C, Djerada Z, Flechtner I, Treluyer JM, Scharfmann R, Cavé H, Vaivre-Douret L, Polak M; GlidKir Study Group.
Diabetes Care. 2015 Nov;38(11):2033-41

• « Toxicologie clinique et analytique des opiacés, de la cocaïne et des amphétamines »

Feliu C, Fouley A, Millart H, Gozalo C, Marty H, Djerada Z.
Ann Biol Clin (Paris). 2015 Jan-Feb;73(1):54-69

• « Population pharmacokinetics of nefopam in elderly, with or without renal impairment, and its link to treatment response.»

Djerada Z, Fournet-Fayard A, Gozalo C, Lelarge C, Lamiable D, Millart H, Malinovsky JM.
Br J Clin Pharmacol. 2014 Jun;77(6):1027-38

• « Validation of a fast method for quantitative analysis of elvitegravir, raltegravir, maraviroc, etravirine, tenofovir, boceprevir and 10 other antiretroviral agents in human plasma samples with a new UPLC-MS/MS technology. »

Djerada Z, Feliu C, Tournois C, Vautier D, Binet L, Robinet A, Marty H, Gozalo C, Lamiable D, Millart H.
J Pharm Biomed Anal. 2013 Dec;86:100-11

• « Agranulocytosis induced by proton-pump inhibitors »

Dury S, Nardi J, Gozalo C, Lebargy F, Deslee G.
J Clin Gastroenterol. 2012 Nov-Dec;46(10):859

• « Pharmacogenetics of toxicity, plasma trough concentration and treatment outcome with nevirapine-containing regimen in anti-retroviral-naïve HIV-infected adults: an exploratory study of the TRIANON ANRS 081 trial.»

Gozalo C, Gérard L, Loiseau P, Morand-Joubert L, Peytavin G, Molina JM, Dellamonica P, Becquemont L, Aboulker JP, Launay O, Verstuyft C 
Basic Clin Pharmacol Toxicol. 2011 Dec;109(6):513-20.

• « Evaluation of the Architect tacrolimus assay in kidney, liver, and heart transplant recipients.»

Bazin C, Guinedor A, Barau C, Gozalo C, Grimbert P, Duvoux C, Furlan V, Massias L, Hulin A.
J Pharm Biomed Anal. 2010 Dec 1;53(4):997-1002

• « French clinical practice guidelines on the management of patients on vitamin k antagonists in at-risk situations (overdose, risk of bleeding and active bleeding) »

Pernod G, Godier A, Gozalo C, Tremey B, Sié P. 
Thrombosis Research, 2010 

• « The polymorphism Trp719Arg in the kinesin-like protein 6 is associated with the presence of late outgrowth endothelial progenitor cells in acute myocardial infarction »

Davani S, Gozalo C, Gambert S, Chalmers D, Gambert P, Schiele F, Kantelip JP, Meneveau N. 
Atherosclerosis, 2010 ; 210(1):48-50

• « Determination of articaine in human plasma by liquid chromatography - mass spectrometry and its application in a pharmacokinetic study»

Hoizey G., Lamiable D., Gozalo C., Miric T., Thomas A., Binet L., Oget O., Millart H., Mauprivez C.
Journal of Pharmaceutical and Biomedical Analysis, 2009 ; 49 (4) : 1082-7.

• « Epidémiologie et facteurs de risque hémorragique des traitements par les antivitamines K »

Gozalo C., Pernod G., Sié P.
Sang Thrombose Vaisseaux, 2008, 20(7) : 21-55

• « Surdosages asymptomatiques en  antivitamines K »

Gozalo C., Tremey B., Pernod G., Sié P.
Sang Thrombose Vaisseaux, 2008, 20(7) : 56-68

• « Distribution tissulaire post-mortem du méprobamate : à propos de 8 cas »

Hoizey G., Gozalo C., Canas F., Fornes P., Binet L., Thomas A., Oget O., Millart H., Lamiable D.
Annales de Toxicologie Analytique, 2008 ; 20 (1) : 47 -51

• « Vitamine K epoxide reductase (VKORC1) genetic polymorphism is associated with venous thromboembolism: results from EDITH study »

Lacut K., Larramendy-Gozalo C., Duchemin J., Mercier B., Gourhant L., Mottier D., Becquemont L., Oger E., Verstuyft C.
Journal of thrombosis and Haemostasis, 2007 Oct ; 5(10):2020-4.

• « Comparison of CR36, a new heparan mimetic, and Pentosan Polysulfate in the treatment of prion diseases »

Larramendy-Gozalo C., Barret A., Daudigeos E., Mathieu E., Antonangeli L., Riffet C., Petit E., Papy-Garcia D., Barritault D., Brown P., Deslys J-P. 
Journal of General Virology, 2007,88(Pt3):1062-7.

• « Prion infection-impaired functional blocks identified by proteomics enlighten the targets and the curing pathways of an anti-prion drug »

Chich J-F., Schaeffer B., Bouin A-P., Mouthon F., Labas V., Larramendy C., Deslys J-P., Grosclaude J. 
Biochim Biophys Acta, 2007 Jan; 1774 (1) : 154-67.

• « Genetic polymorphism of Vitamin K epoxide reductase (VKORC1) 1173C>T in a Chinese and a Caucasian population »

Larramendy-Gozalo C., Yang J.Q., Verstuyft C., Bodin L., Dubert L., Zhang Y., Xu C., Fan L., Jaillon P., Becquemont L. 
Basic and Clinical Pharmacology and Toxicology, 2006 Jun ; 98 (6) : 611-3.

• « Intérêt des différents marqueurs biologiques du tabagisme dans la prise en charge du fumeur » 

Larramendy C., Asnafi-Farhang S., Lagrue G., Diviné C.
Pathol Biol (Paris). 2004 Apr ; 52 (3) : 164-72.

• «TaqMan PCR-based gene dosage assay for predictive testing in individuals from a cancer family with INK4 locus haploinsufficiency»

Laurendeau I., Bahuau M., Vodovar N., Larramendy C., Olivi M., Vidaud M., Vidaud D.
Clin Chem 1999 Jul ; 45 (7) : 982-6

Publications 

• « Urinary methotrexate dosage in rheumatoid arthritis, in patients treated for at least 6 months: a potential marker of adherence. »

Théate N, Geoffroy M, Kanagaratnam L, Gozalo C, Charlot I, Bolko L, Hittinger-Roux A, Djerada Z, Salmon JH.
RMD Open. 2024 May 20;10(2):e004024. doi: 10.1136/rmdopen-2023-004024.PMID: 38772677 

• « Simultaneous quantification of 55 psychotropic drugs and metabolites in human plasma with a fast UPLC-MS/MS method. »

Konecki C, Hadjoudj J, Tralongo F, Haudecoeur C, Gozalo C, Fouley A, Marty H, Feliu C, Djerada Z..
Biomed Pharmacother. 2023 Dec 31;169:115918. doi: 10.1016/j.biopha.2023.115918. Epub 2023 Nov 25.PMID: 38007935 

• « A new pharmacokinetic model of urinary methotrexate to assess adherence in rheumatoid arthritis »

Geoffroy M, Gozalo C, Konecki C, Pauvele L, Hittinger A, Pastorel N, Feliu C, Salmon JH, Djerada Z.
Biomed Pharmacother. 2023 Oct 19 ;168:115620. doi: 10.1016/j.biopha.2023.115620. Online ahead of print.

• « Renal impairment and abnormal liver function tests in pre-therapeutic phenotype-based DPD deficiency screening using uracilemia : a comprehesive population-based study in 1138 patients »

Callon S, Brugel M, Botsen D, Royer B, Slimano F, Feliu C, Gozalo C, Konecki C, Devie B, Carlier C, Daire V, Laurès N, Perrier M, Djerada Z, Bouche O.
Ther Adv Med Oncol. 2023 Jan 10;15:17588359221148536. doi: 10.1177/17588359221148536. eCollection 2023. 

• « Incidence, associated factors,and effect on renal function of amoxicillin crystalluria in patients receiving high doses of amoxicillin (The Cristamox study) : a cohort study »

Demotier S, Limelette A, Charmillon A, Baux E, Parent X, Mestrallet S, Pavel S, Servettaz A, Dramé M, Muggeo A, Wynckel A, Gozalo C, Taam MA, Fillion A, Jaussaud R, Trenque T, Piroth L, Bani-Sadr F, Hentzien M ; Cristamox study-group.
EClinicalMedicine. 2022 Mar 12 ;45 ;101340

• « Alveolar hemorrhage due to marijuana smokingusing water pipe made with plastic bottle: casereport and narrative review of the literature »

Toquet S, Cousson J, Choiselle N, Gozalo C, Giusti D, Bani-Sadr F, N’Guyen Y.
Inhalation Toxicology, DOI: 10.1080/08958378.2021.1939465

• « Evaluation of the pharmacokinetics of glibenclamide tablet given, off label, orally to children suffering from neonatal syndromic hyperglycemia. »

Bouazza N, Djerada Z, Gozalo C, Busiah K, Beltrand J, Berdugo M, Urien S, Treluyer JM, Polak M.
Eur J Clin Pharmacol. 2016 Nov;72(11):1373-1379

• « Pharmacogenetics of toxicity, plasma trough concentration and treatment outcome with nevirapine-containing regimen in anti-retroviral-naïve HIV-infected adults: an exploratory study of the TRIANON ANRS 081 trial.»

Gozalo C, Gérard L, Loiseau P, Morand-Joubert L, Peytavin G, Molina JM, Dellamonica P, Becquemont L, Aboulker JP, Launay O, Verstuyft C 
Basic Clin Pharmacol Toxicol. 2011 Dec;109(6):513-20.

• « French clinical practice guidelines on the management of patients on vitamin k antagonists in at-risk situations (overdose, risk of bleeding and active bleeding) »

Pernod G, Godier A, Gozalo C, Tremey B, Sié P. 
Thrombosis Research, 2010 

• « Vitamine K epoxide reductase (VKORC1) genetic polymorphism is associated with venous thromboembolism: results from EDITH study »

Lacut K., Larramendy-Gozalo C., Duchemin J., Mercier B., Gourhant L., Mottier D., Becquemont L., Oger E., Verstuyft C.
Journal of thrombosis and Haemostasis, 2007 Oct ; 5(10):2020-4.